What you eat plays a big role in how you look and feel. We want vegans to look and feel their best, so in this video, you’ll learn 5 …
What you eat plays a big role in how you look and feel. We want vegans to look and feel their best, so in this video, you’ll learn 5 …
© 2021 OlyaBrand
Good stuff guys!
The answer to why many people don't seem to have any oxalate issues with dark greens, may be due to having a healthy gut microbiome. We know the microbiome changes when our diet changes. Eating more oxalates (and fiber) increases oxalate consuming bacteria and conversely consuming less fiber results in less oxalate digesting bacteria. Study: "Reducing the concentration of oxalate in the medium reduced the numbers of Oxalobacter formigenes bacteria."
With a hi fiber diet feeding (prebiotic) O. formigenes, their metabolization of oxalates may make oxalates a non-issue for nutrient absorption in those consuming a whole food, plant-exclusive diet. Eating animal foods lowers O. formigenes, both from reduced fiber intake and from increasing competitive pathogenic bacteria, creating dysbiosis.
Oxalate research shows that:
1. Where does it come from? Oxalic acid is mostly produced endogenously by human metabolism and less than half comes from our diet.
2. From study below: “O. formigenes degraded up to 98% of available oxalate in vitro and also promotes endogenous oxalate secretion”
3. Introducing human oxalate-consuming bacteria reversed oxalate risk: "Remarkably, colonization…resulted in a normalization of the hyperoxaluria and hyperoxalemia exhibited in non-colonized counterparts."
4. "…Oxalobacter (oxalate-eating bacteria) colonization led to reductions in urinary excretion."
5. That the use of anti-biotics can wipe out these good oxalate-eating bacteria: "The therapeutic use of antibiotics and other drugs may contribute to the loss of Oxalobacter formigenes."
6. A high fiber diet increases Oxalobacter and a diet of animal protein and fat increases pathogenic Bacteroides, which decreases Oxalobacter.
7. Replacing the good bacteria in our gut, cancels any negative effects – in just ONE DOSE of Oxalobacter! Study: "A single oral ingestion of O. formigenes by adult volunteers was, for the first time, shown to result in (i) reduced urinary oxalate excretion following administration of an oxalate load…"
8. That oxalate uptake from our gut into the bloodstream is regulated by human cells communicating to oxalate-consuming microbiota: "However, the precise signaling molecules and pathways involved in this physiological bacteria-host interaction have yet to be elucidated."
Study: "Gut microbiota and oxalate homeostasis"
Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5300851/
Study: “Oxalobacter formigenes may reduce the risk of calcium oxalate kidney stones”
“…only 17% of 247 stone subjects were colonized with O. formigenes…”
Link: https://pubmed.ncbi.nlm.nih.gov/18322162/
Study: "Oxalobacter formigenes and Its Potential Role in Human Health"
Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC124017/
Study: “The Use of Antibiotics and Risk of Kidney Stones"
"Recent evidence suggests a possible, causal role of antibiotics in the development of kidney stones. A possible explanation for this finding includes alterations in the microbiome, especially in oxalate-degrading bacteria like O. formigenes."
Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662656/
Study: "Antibiotic Use and Risk of Incident Kidney Stones in Female Nurses"
"Results: Cumulative use of antibiotics for a total of 2 or more months during the age range of 40 to 49 years (NHS II) and 40 to 59 years (NHS II) was associated with significantly higher risk for developing incident stones compared with no use (pooled HR, 1.48; 95% CI, 1.12-1.96)." Link: https://pubmed.ncbi.nlm.nih.gov/31543288/
Study: “Oxalate-degrading bacteria of the human gut as probiotics in the management of kidney stone disease.”
Link: https://pubmed.ncbi.nlm.nih.gov/20602988/
Good video!
THe third point you make about eating clean is so important. People confuse the goals. If you are trying to get your dream body, then although eating clean is important for your health, it doesn't necessarily contribute to your strength and fitness. @10:36 "clean eating is not the solution to building the body of your dreams. However, eating most of your calories from healthy, nutritious foods is important for your health." Well said, @leif